Columbia, MD -- Optical methods such as UV/Vis or NIR spectroscopy can be very powerful tools for analyzing a range of product characteristics, but in processes involving wet and sticky powders it is necessary to ensure that the system has a clear view of the product. Conventional windows used in process equipment such as fluid bed systems, high shear granulators or spray dryers have always suffered from the risk of window fouling. The new Lighthouse Probe™ has overcome this problem.
In addition to in-process cleaning (CIP), to ensure a clear optical path, the Lighthouse Probe has been designed to enable the probe and wash system, including the critical product seal area, to be fully cleaned in place (CIP – Clean-In-Place) at the end of the process. The novel design also includes a self calibration facility which can be used to positively confirm that the seven observation windows have not become contaminated and also to regularly check the calibration of the spectrometer.
The Lighthouse Probe uses a combination of fiber optics and mirrors to give an exceptionally compact design suitable for simple mounting on the smallest processors without disrupting the process. At the same time it offers the ability to ensure that the analyzed sample volume is consistent with the scale of scrutiny required with respect to a unit dosage.
GEA Pharma Systems will now offer the Lighthouse Probe Technology as part of its process equipment and will continue to use its extensive background in process engineering to develop new applications. This will enable GEA Pharma Systems to offer world-class solutions to meet the demands for pharmaceutical production in the 21st century.
Options to retrofit to existing process equipment are also available.
